HSE’s Asthmagen compendium reports evidence from occupational surveys and specific bronchial-challenge studies that psyllium can cause occupational asthma, with immunological evidence including psyllium-specific IgE and positive skin-prick tests; it concludes that psyllium meets the criteria for classification as a respiratory sensitiser.
page 131 · C43: Psyllium — Summary and conclusion · 1
Evidence is available from 3 surveys of occupationally exposed subjects indicating that psyllium can cause occupational asthma. These observations are consistent with clear positive results obtained in five specific bronchial challenge studies following psyllium exposure. The mechanism appeared to be immunological, as indicated by the presence of psyllium specific IgE and positive skin prick tests to psyllium.